Domingo Quinones was born on August 9, 1963 in Perth Amboy, New Jersey. When he was four years old he moved to Puerto Rico with his parents and lived in Ceiba, Puerto Rico. He returned to New York City in 1977. He began his career there six years later with the Conjunto Nativo. He also performed with other groups, including the orchestra of Rafael de Jesús, with José Alberto “El Canario”, with Johnny Rodriguez and the Conjunto Clásico.
In 1985 he replaced Roberto Lugo in the orchestra of Luis “Perico” Ortiz with whom he recorded four albums, including La vida en broma (1985), In Tradition (1986) and Perico (1987). He then sang for a time with Louie Ramirez and Roberto Roena.
In 1990, he signed as a solo artist with RMM and released his first solo album: Domingo es mi nombre. After joining Tito Puente on his 100th record, Quiñones released his second solo album Pintando Lunas. That album included a duet entitled “Dos Amigos” with Tony Vega and a salsa version of the song “Crazy for You” which proved his great versatility.